PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in. Medscape – Indication-specific dosing for Durezol, (difluprednate), frequency- based contraindications, pregnancy & lactation schedules, and cost information. Medscape prescription drug monographs are based on FDA- approved labeling. USP) tablets. Full Prescribing Information, including Boxed WARNING Durezol. (difluprednate ophthalmic emulsion) %. Full Prescribing Information. E.

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Wear sunglasses if this medicine makes your eyes more sensitive to sunlight. If ocular signs and symptoms fail to improve after 2 days, the patient should be re-evaluated. Difluprednate is classified as pregnancy category C.

When prescribing a steroid to treat inflammation and pain associated with ocular surgery, and for the treatment of endogenous anterior uveitis. Do not use the medicine more often than directed. Corticosteroids are associated with the presence of extracellular glycosaminoglycans in ocular trabecular cells, which have been hypothesized to increase the resistance of aqueous outflow.

Present this offer and your insurance card along with a valid prescription at any participating pharmacy or through mail order. Difluprednate should be used with caution in patients with a corneal abrasion.

Age restrictions may apply. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, deposition of collagen, and scar formation associated with inflammation. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Shake well before using. Infants, Children, and Adolescents. This medicine is only for you. In acute purulent conditions, steroids may mask infection or enhance existing infection.


Cataracts — Use of corticosteroids may result in posterior subcapsular cataract formation. What should I watch for while using this medicine? Do not take by mouth.

Difluprednate is also contraindicated in any mycobacterial infection of the eye or fungal infection of ocular structures. Bacterial infections — Prolonged use of corticosteroids may suppress the host response and thus increase the hazard pgescribing secondary ocular infections.

Difluprednate is contraindicated in individuals with glycerin hypersensitivity, hypersensitivity to difluprednate, corticosteroid hypersensitivity, polysorbate 80 ihformation, or any of the other product ingredients boric acid, castor oil, polysorbate 80, sodium acetate, sodium EDTA, sodium hydroxide.

Ophthalmic corticosteroid Used for postoperative ocular pain and inflammation and endogenous anterior uveitis Safety and efficacy comparable to betamethasone 0.

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Wash your hands before and after use. Fungal invasion should be evaluated in any persistent corneal ulceration where corticosteroid treatment has been used. Special care may be needed. There is no generally accepted explanation for the exact mechanism of prexcribing for ocular corticosteroids.

This list may not describe all possible side effects. You should not wear contact lenses while using this medicine. Questions should be directed to: Patients with diabetes mellitus appear to be more susceptible to developing PSC cataracts during ocular steroid use. Home Shopping cart Checkout Articles.


If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Keep out of the reach of children. Select your medication below to get started.

To further minimize the amount of drug that reaches the systemic circulation and breast milk, predcribing pressure over the tear duct by the corner of the eye for 1 ddurezol after ophthalmic administration. Dosage and Administration For the treatment of inflammation and pain associated with ocular surgery instill one drop into the conjunctival sac of the affected eye 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response.

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Fungal cultures should be taken when appropriate. All trademarks and registered trademarks are the property of their respective owners. We do not record any personal information entered above. Call your doctor for medical advice about side effects.